{"id":27794,"date":"2020-10-07T18:51:36","date_gmt":"2020-10-07T16:51:36","guid":{"rendered":"http:\/\/dorogimedence.hu\/?p=27794"},"modified":"2020-10-08T09:05:01","modified_gmt":"2020-10-08T07:05:01","slug":"magyarorszagnak-is-van-covid-elleni-gyogyszere","status":"publish","type":"post","link":"https:\/\/dorogimedence.hu\/index.php\/2020\/10\/07\/magyarorszagnak-is-van-covid-elleni-gyogyszere\/","title":{"rendered":"Magyarorsz\u00e1gnak is van Covid elleni gy\u00f3gyszere"},"content":{"rendered":"

A Richter Gedeon Nyrt. sikeresen szintetiz\u00e1lta a koronav\u00edrus kezel\u00e9s\u00e9re szolg\u00e1l\u00f3 Remdesivir-t.<\/strong><\/p>\n

A Richtern\u00e9l jelenleg \u00f6t olyan kutat\u00e1s fejleszt\u00e9si t\u00e9ma is fut, amelynek c\u00e9lja a Covid gy\u00f3gy\u00edt\u00e1s\u00e1t szolg\u00e1l\u00f3 ter\u00e1pia kifejleszt\u00e9se vagy nagy\u00fczemi gy\u00e1rt\u00e1sa. Ezek egy r\u00e9sz\u00e9ben az egyetemi h\u00e1torsz\u00e1g tudom\u00e1nyos inputj\u00e1ra is t\u00e1maszkodnak, illetve a korm\u00e1nyzat anyagi t\u00e1mogat\u00e1s\u00e1ra. Ezek k\u00f6z\u00fcl t\u00f6bb olyan is van, mely biotechnol\u00f3giai projekt. Ezekben az esetekben a hat\u00f3anyag el\u0151\u00e1ll\u00edt\u00e1sa a Richter 2012-ben \u00e1tadott debreceni biotechnol\u00f3giai \u00fczem\u00e9ben t\u00f6rt\u00e9nik, illetve a budapesti szintetikus gy\u00e1rt\u00e1si kapacit\u00e1suk ig\u00e9nybev\u00e9tel\u00e9vel val\u00f3sul meg.<\/p>\n

A jelenleg fut\u00f3 projektek az al\u00e1bbiak:<\/strong><\/p>\n

    \n
  1. A Richter b\u00fcszke arra, hogy mintegy \u00f6t h\u00f3nap megfesz\u00edtett munka eredm\u00e9nyek\u00e9nt sikeresen megoldott\u00e1k a jelenleg \u2013 s\u00falyos st\u00e1diumban l\u00e9v\u0151 COVID betegek kezel\u00e9se \u2013 leghat\u00e9konyabbnak bizonyul\u00f3 remdesivir hat\u00f3anyag szint\u00e9zis\u00e9t, melyet sikeresen le is gy\u00e1rtottak. A legy\u00e1rtott mennyis\u00e9g kb. 3000 k\u00f3rh\u00e1zi beteg kezel\u00e9s\u00e9t teszi lehet\u0151v\u00e9 remdesivir-rel, mely ezid\u00e1ig az els\u0151 olyan szer, mely klinikailag igazoltan gyors\u00edtja a betegek gy\u00f3gyul\u00e1s\u00e1t \u00e9s trendszer\u0171en cs\u00f6kkenti a hal\u00e1loz\u00e1si r\u00e1t\u00e1t. A szeptemberben m\u00e1r min\u0151s\u00e9gellen\u0151rz\u00e9si vizsg\u00e1laton \u00e1tesett \u00e9s \u00edgy felszabad\u00edtott injekci\u00f3 form\u00e1ban kiszerelt hat\u00f3anyag kb.: 260 k\u00f3rh\u00e1zi beteg kezel\u00e9s\u00e9t teszi lehet\u0151v\u00e9, mely mennyis\u00e9get ezt k\u00f6vet\u0151en folyamatosan tudj\u00e1k n\u00f6velni. A m\u00e9g h\u00e1tral\u00e9v\u0151 klinikai vizsg\u00e1latok lebonyol\u00edt\u00e1sa nem a Richter feladata.<\/li>\n
  2. A Richter tagja annak a konzorciumnak is, mely a jap\u00e1n favipiravir hat\u00f3anyag hazai fejleszt\u00e9s\u00e9t t\u0171zte ki c\u00e9lul, ez a projekt is jelenleg folyamatban van. Itt a Richter hat\u00f3anyaggy\u00e1rt\u00e1s ter\u00fclet\u00e9n \u00e9rintett.<\/li>\n
  3. Egy biotechnol\u00f3giai \u00faton el\u0151\u00e1ll\u00edtott un. bioszimil\u00e1ris tocilizumab nev\u0171 hat\u00f3anyag fejleszt\u00e9si, gy\u00e1rt\u00e1si \u00e9s \u00e9rt\u00e9kes\u00edt\u00e9si jogait m\u00e1r kor\u00e1bban megszerezte a Richter. A tocilizumab alapvet\u0151en reumatol\u00f3giai indik\u00e1ci\u00f3ban alkalmazott biologikum, de felvet\u0151d\u00f6tt a haszn\u00e1lata a COVID betegek kezel\u00e9s\u00e9re, akik a v\u00edrus fert\u0151z\u00e9s k\u00f6vetkezm\u00e9nyek\u00e9pp gyullad\u00e1sos t\u00fcneteket mutatnak.<\/li>\n
  4. A t\u00e1rsas\u00e1g \u00e9rdekelts\u00e9ge az olt\u00f3anyag gy\u00e1rt\u00e1sban a Richter-Helm Biologics-szal, azaz a Helm AG-val k\u00f6z\u00f6s tulajdon\u00fa v\u00e1llalatukon kereszt\u00fcl van. Az USA-ban bejegyzett INOVIO-val m\u00e9g \u00e1prilisban k\u00f6t\u00f6ttek meg\u00e1llapod\u00e1st az INOVIO COVID-19 elleni DNS-alap\u00fa olt\u00f3anyag\u00e1nak gy\u00e1rt\u00e1s\u00e1ra. Ez a vakcina jelenleg m\u00e9g fejleszt\u00e9s alatt \u00e1ll, v\u00e1rhat\u00f3an az \u00e9v v\u00e9ge el\u0151tt l\u00e9p F\u00e1zis 3 klinikai szakaszba.<\/li>\n
  5. A Richter tagja ugyanakkor annak a konzorciumnak is, mely eredeti biotechnol\u00f3giai gy\u00f3gyszer fejleszt\u00e9s keret\u00e9ben keres ter\u00e1pi\u00e1s megold\u00e1st a COVID kezel\u00e9s\u00e9re. Az un. ACE2-f\u00fazi\u00f3s f\u00fazi\u00f3s feh\u00e9rje szint\u00e9n COVID betegek kezel\u00e9s\u00e9re szolg\u00e1l\u00f3 k\u00e9sz\u00edtm\u00e9ny lehet, a feh\u00e9rje v\u00e1rhat\u00f3an egyfel\u0151l k\u00e9pes lesz semleges\u00edteni a v\u00edrust, m\u00e1sfel\u0151l a v\u00edrus \u00e1ltal megfert\u0151z\u00f6tt sejteket is elpuszt\u00edtja az \u00e1ltala beind\u00edtott immunv\u00e1lasz r\u00e9v\u00e9n. Ez egy igen korai f\u00e1zisban l\u00e9v\u0151 fejleszt\u00e9s, mely m\u00e9g tov\u00e1bbi preklinikai \u00e9s klinikai vizsg\u00e1latokat ig\u00e9nyel, a piaci bevezet\u00e9s sikeres vizsg\u00e1latok eset\u00e9n v\u00e1rhat\u00f3an m\u00e9g t\u00f6bb \u00e9v. Ennek a feh\u00e9rj\u00e9nek a fejleszt\u00e9s\u00e9t n\u00e9gy int\u00e9zm\u00e9ny kutat\u00f3ib\u00f3l \u00e9s gy\u00f3gyszerfejleszt\u0151ib\u0151l \u00e1ll\u00f3 konzorcium v\u00e9gzi. Az egy\u00fcttm\u0171k\u00f6d\u00e9s az E\u00f6tv\u00f6s Lor\u00e1nd Tudom\u00e1nyegyetem, a P\u00e9csi Tudom\u00e1nyegyetem, az ImmunoGenes Kft., valamint a Richter Gedeon Nyrt. k\u00f6z\u00f6s v\u00e1llalkoz\u00e1sa, melyet az \u00e1llam t\u00e1mogat. A konzorciumot az ELTE Term\u00e9szettudom\u00e1nyi Kar Immunol\u00f3giai Tansz\u00e9ke vezeti, melynek \u00e9l\u00e9n Kacskovics Imre professzor \u00e1ll.<\/li>\n<\/ol>\n

    Fontos hangs\u00falyozni, hogy a fejleszt\u00e9si projektjeik egy\u00e9rtelm\u0171en ter\u00e1pia f\u00f3kusz\u00faak, azaz koronav\u00edrus-fert\u0151z\u00e9s kezel\u00e9s\u00e9re ir\u00e1nyulnak. Ami olt\u00f3anyag fejleszt\u00e9s\u00e9t ill. gy\u00e1rt\u00e1s\u00e1t illeti, a Richternek ez nem profilja, ezen a ter\u00fcleten nincs hagyom\u00e1nyos tud\u00e1suk, \u00e9s nincs is saj\u00e1t fejleszt\u00e9si projekt\u00fcnk. \u00cdgy a vakcina v\u00e1rhat\u00f3 el\u00e9rhet\u0151s\u00e9g\u00e9r\u0151l nem is tudnak nyilatkozni.<\/p>\n

    A j\u00e1rv\u00e1nyhelyzet egy\u00e9rtelm\u0171en visszaigazolta a Richter vertik\u00e1lisan integr\u00e1lt \u00fczleti modellj\u00e9nek l\u00e9tjogosults\u00e1g\u00e1t \u00e9s egyben n\u00e9lk\u00fcl\u00f6zhetetlens\u00e9g\u00e9t a hazai betegek stabil gy\u00f3gyszerell\u00e1t\u00e1s\u00e1nak biztos\u00edt\u00e1sa szempontj\u00e1b\u00f3l. Ez az \u00fczleti modell teszi lehet\u0151v\u00e9 azt, hogy a kutat\u00e1s fejleszt\u00e9s, a hat\u00f3anyag \u00e9s k\u00e9sz term\u00e9k gy\u00e1rt\u00e1s, valamint minden tov\u00e1bbi piacra jut\u00e1st megel\u0151z\u0151 f\u00e1zisa a gy\u00e1rt\u00e1si disztrib\u00faci\u00f3s l\u00e1ncnak Magyarorsz\u00e1gon t\u00f6rt\u00e9njen, ez\u00e1ltal teljes f\u00fcggetlens\u00e9get biztos\u00edtva k\u00fclf\u00f6ldi forr\u00e1sokt\u00f3l. Ez nem csup\u00e1n a biztons\u00e1gos ell\u00e1t\u00e1s szempontj\u00e1b\u00f3l meghat\u00e1roz\u00f3, hanem kiemelked\u0151 jelent\u0151s\u00e9ggel b\u00edr a nemzetgazdas\u00e1g hozz\u00e1j\u00e1rul\u00e1s szempontj\u00e1b\u00f3l is.<\/p>\n

    Forr\u00e1s: Richter Gedeon Nyrt.
    \n<\/em><\/p>\n

    Bor\u00edt\u00f3k\u00e9p: polygraph.info<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

    A Richter Gedeon Nyrt. sikeresen szintetiz\u00e1lta a koronav\u00edrus kezel\u00e9s\u00e9re szolg\u00e1l\u00f3 Remdesivir-t. A Richtern\u00e9l jelenleg \u00f6t olyan kutat\u00e1s fejleszt\u00e9si t\u00e9ma is fut, amelynek c\u00e9lja a Covid gy\u00f3gy\u00edt\u00e1s\u00e1t szolg\u00e1l\u00f3 ter\u00e1pia kifejleszt\u00e9se vagy nagy\u00fczemi gy\u00e1rt\u00e1sa. Ezek egy r\u00e9sz\u00e9ben az egyetemi h\u00e1torsz\u00e1g tudom\u00e1nyos inputj\u00e1ra is t\u00e1maszkodnak, illetve a korm\u00e1nyzat anyagi t\u00e1mogat\u00e1s\u00e1ra. Ezek k\u00f6z\u00fcl t\u00f6bb olyan is van, mely biotechnol\u00f3giai<\/p>\n","protected":false},"author":1,"featured_media":27795,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3],"tags":[4738,4060,4771],"class_list":{"0":"post-27794","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-hirek","8":"tag-koronavirus","9":"tag-richter","10":"tag-richter-gedeon-nyrt"},"yoast_head":"\nMagyarorsz\u00e1gnak is van Covid elleni gy\u00f3gyszere<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dorogimedence.hu\/index.php\/2020\/10\/07\/magyarorszagnak-is-van-covid-elleni-gyogyszere\/\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:type\" content=\"article\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:title\" content=\"Magyarorsz\u00e1gnak is van Covid elleni gy\u00f3gyszere\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:description\" content=\"A Richter Gedeon Nyrt. sikeresen szintetiz\u00e1lta a koronav\u00edrus kezel\u00e9s\u00e9re szolg\u00e1l\u00f3 Remdesivir-t. A Richtern\u00e9l jelenleg \u00f6t olyan kutat\u00e1s fejleszt\u00e9si t\u00e9ma is fut, amelynek c\u00e9lja a Covid gy\u00f3gy\u00edt\u00e1s\u00e1t szolg\u00e1l\u00f3 ter\u00e1pia kifejleszt\u00e9se vagy nagy\u00fczemi gy\u00e1rt\u00e1sa. Ezek egy r\u00e9sz\u00e9ben az egyetemi h\u00e1torsz\u00e1g tudom\u00e1nyos inputj\u00e1ra is t\u00e1maszkodnak, illetve a korm\u00e1nyzat anyagi t\u00e1mogat\u00e1s\u00e1ra. Ezek k\u00f6z\u00fcl t\u00f6bb olyan is van, mely biotechnol\u00f3giai\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dorogimedence.hu\/index.php\/2020\/10\/07\/magyarorszagnak-is-van-covid-elleni-gyogyszere\/\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:site_name\" content=\"Dorogi-medence Region\u00e1lis H\u00edrport\u00e1l\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/dorogimedence\/\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-07T16:51:36+00:00\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-08T07:05:01+00:00\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/dorogimedence.hu\/wp-content\/uploads\/2020\/10\/koronavirus.jpg?fit=830%2C450&ssl=1\" class=\"yoast-seo-meta-tag\" \/>\n\t<meta property=\"og:image:width\" content=\"830\" 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